Chasing notifiable avian influenza in domestic poultry: a case report of low-pathogenic avian influenza h5 viruses in two Belgian holdings.
Identifieur interne : 000040 ( Main/Exploration ); précédent : 000039; suivant : 000041Chasing notifiable avian influenza in domestic poultry: a case report of low-pathogenic avian influenza h5 viruses in two Belgian holdings.
Auteurs : S. Marché [Belgique] ; S. Van Borm ; B. Lambrecht ; P. Houdart ; T. Van Den BergSource :
- Transboundary and emerging diseases [ 1865-1682 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Belgique (épidémiologie), Flambées de maladies (médecine vétérinaire), Grippe chez les oiseaux (virologie), Grippe chez les oiseaux (épidémiologie), Maladies de la volaille (virologie), Maladies de la volaille (épidémiologie), Oiseaux, Sous-type H5N2 du virus de la grippe A (isolement et purification), Sous-type H5N2 du virus de la grippe A (pathogénicité), Test ELISA (médecine vétérinaire), Tests d'hémagglutination (médecine vétérinaire).
- MESH :
- isolement et purification : Sous-type H5N2 du virus de la grippe A.
- médecine vétérinaire : Flambées de maladies, Test ELISA, Tests d'hémagglutination.
- pathogénicité : Sous-type H5N2 du virus de la grippe A.
- virologie : Grippe chez les oiseaux, Maladies de la volaille.
- épidémiologie : Belgique, Grippe chez les oiseaux, Maladies de la volaille.
- Animaux, Oiseaux.
English descriptors
- KwdEn :
- Animals, Belgium (epidemiology), Birds, Disease Outbreaks (veterinary), Enzyme-Linked Immunosorbent Assay (veterinary), Hemagglutination Tests (veterinary), Influenza A Virus, H5N2 Subtype (isolation & purification), Influenza A Virus, H5N2 Subtype (pathogenicity), Influenza in Birds (epidemiology), Influenza in Birds (virology), Poultry Diseases (epidemiology), Poultry Diseases (virology).
- MESH :
- epidemiology : Belgium, Influenza in Birds, Poultry Diseases.
- isolation & purification : Influenza A Virus, H5N2 Subtype.
- pathogenicity : Influenza A Virus, H5N2 Subtype.
- veterinary : Disease Outbreaks, Enzyme-Linked Immunosorbent Assay, Hemagglutination Tests.
- virology : Influenza in Birds, Poultry Diseases.
- Animals, Birds.
Abstract
In December 2008, bird species in two geographically distant holdings were found positive for H5 viruses following the annual Avian influenza serological screening in Belgium. The virological tests performed identified in one holding a low-pathogenic avian influenza (LPAI) virus subtype H5N2, and a H5 LPAI virus was identified by real-time PCR and direct sequencing at the second holding. The first farm was an outdoor mixed holding housing ornamental birds and poultry (n = 6000) and the second a free-range geese breeding farm (n = 1500). No clinical signs or mortalities were reported. Control measures defined by Council Directive 2005/94/EC were followed, including notification to the European Commission via the Animal Disease Notification System and to the World Organization for Animal Health, and poultry were killed, while ornamental bird species were quarantined. Partial sequencing of the H5N2 virus haemagglutinin and neuraminidase N2 gene sequences revealed a close homology to some recent LPAI isolates identified from wild birds in Germany and Italy and from wild birds in Eurasia and Africa, respectively. It is noteworthy that, these two holdings were already H5 positive based on HI test results carried out during the previous serological screening; however, no virus was detected at that time. To have a better understanding of the potential 'silent' circulation of the H5N2 isolate in the field, experimental infections of chickens and turkeys were performed. The low excretion detected might in part explain viral persistence not associated with spread between gallinaceous birds in the same holding, indicating that the H5N2 LPAI isolate was not fully adapted to these two poultry species. Our results highlighted limitations to only using serological screening for the early detection of LPAI in an 'at-risk farm', suggesting that virological and serological monitoring tests be applied simultaneously as a means of testing animals in 'at-risk farms'.
DOI: 10.1111/tbed.12056
PubMed: 23347839
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Van Den Berg</name></author></analytic><series><title level="j">Transboundary and emerging diseases</title><idno type="eISSN">1865-1682</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Belgium (epidemiology)</term><term>Birds</term><term>Disease Outbreaks (veterinary)</term><term>Enzyme-Linked Immunosorbent Assay (veterinary)</term><term>Hemagglutination Tests (veterinary)</term><term>Influenza A Virus, H5N2 Subtype (isolation & purification)</term><term>Influenza A Virus, H5N2 Subtype (pathogenicity)</term><term>Influenza in Birds (epidemiology)</term><term>Influenza in Birds (virology)</term><term>Poultry Diseases (epidemiology)</term><term>Poultry Diseases (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Belgique (épidémiologie)</term><term>Flambées de maladies (médecine vétérinaire)</term><term>Grippe chez les oiseaux (virologie)</term><term>Grippe chez les oiseaux (épidémiologie)</term><term>Maladies de la volaille (virologie)</term><term>Maladies de la volaille (épidémiologie)</term><term>Oiseaux</term><term>Sous-type H5N2 du virus de la grippe A (isolement et purification)</term><term>Sous-type H5N2 du virus de la grippe A (pathogénicité)</term><term>Test ELISA (médecine vétérinaire)</term><term>Tests d'hémagglutination (médecine vétérinaire)</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Belgium</term><term>Influenza in Birds</term><term>Poultry Diseases</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Influenza A Virus, H5N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Sous-type H5N2 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Flambées de maladies</term><term>Test ELISA</term><term>Tests d'hémagglutination</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Influenza A Virus, H5N2 Subtype</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Sous-type H5N2 du virus de la grippe A</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Disease Outbreaks</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Hemagglutination Tests</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Grippe chez les oiseaux</term><term>Maladies de la volaille</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza in Birds</term><term>Poultry Diseases</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Belgique</term><term>Grippe chez les oiseaux</term><term>Maladies de la volaille</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Birds</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Oiseaux</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In December 2008, bird species in two geographically distant holdings were found positive for H5 viruses following the annual Avian influenza serological screening in Belgium. The virological tests performed identified in one holding a low-pathogenic avian influenza (LPAI) virus subtype H5N2, and a H5 LPAI virus was identified by real-time PCR and direct sequencing at the second holding. The first farm was an outdoor mixed holding housing ornamental birds and poultry (n = 6000) and the second a free-range geese breeding farm (n = 1500). No clinical signs or mortalities were reported. Control measures defined by Council Directive 2005/94/EC were followed, including notification to the European Commission via the Animal Disease Notification System and to the World Organization for Animal Health, and poultry were killed, while ornamental bird species were quarantined. Partial sequencing of the H5N2 virus haemagglutinin and neuraminidase N2 gene sequences revealed a close homology to some recent LPAI isolates identified from wild birds in Germany and Italy and from wild birds in Eurasia and Africa, respectively. It is noteworthy that, these two holdings were already H5 positive based on HI test results carried out during the previous serological screening; however, no virus was detected at that time. To have a better understanding of the potential 'silent' circulation of the H5N2 isolate in the field, experimental infections of chickens and turkeys were performed. The low excretion detected might in part explain viral persistence not associated with spread between gallinaceous birds in the same holding, indicating that the H5N2 LPAI isolate was not fully adapted to these two poultry species. Our results highlighted limitations to only using serological screening for the early detection of LPAI in an 'at-risk farm', suggesting that virological and serological monitoring tests be applied simultaneously as a means of testing animals in 'at-risk farms'. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">23347839</PMID><DateCompleted><Year>2015</Year><Month>06</Month><Day>10</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1865-1682</ISSN><JournalIssue CitedMedium="Internet"><Volume>61</Volume><Issue>6</Issue><PubDate><Year>2014</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Transboundary and emerging diseases</Title><ISOAbbreviation>Transbound Emerg Dis</ISOAbbreviation></Journal><ArticleTitle>Chasing notifiable avian influenza in domestic poultry: a case report of low-pathogenic avian influenza h5 viruses in two Belgian holdings.</ArticleTitle><Pagination><MedlinePgn>526-36</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/tbed.12056</ELocationID><Abstract><AbstractText>In December 2008, bird species in two geographically distant holdings were found positive for H5 viruses following the annual Avian influenza serological screening in Belgium. The virological tests performed identified in one holding a low-pathogenic avian influenza (LPAI) virus subtype H5N2, and a H5 LPAI virus was identified by real-time PCR and direct sequencing at the second holding. The first farm was an outdoor mixed holding housing ornamental birds and poultry (n = 6000) and the second a free-range geese breeding farm (n = 1500). No clinical signs or mortalities were reported. Control measures defined by Council Directive 2005/94/EC were followed, including notification to the European Commission via the Animal Disease Notification System and to the World Organization for Animal Health, and poultry were killed, while ornamental bird species were quarantined. Partial sequencing of the H5N2 virus haemagglutinin and neuraminidase N2 gene sequences revealed a close homology to some recent LPAI isolates identified from wild birds in Germany and Italy and from wild birds in Eurasia and Africa, respectively. It is noteworthy that, these two holdings were already H5 positive based on HI test results carried out during the previous serological screening; however, no virus was detected at that time. To have a better understanding of the potential 'silent' circulation of the H5N2 isolate in the field, experimental infections of chickens and turkeys were performed. The low excretion detected might in part explain viral persistence not associated with spread between gallinaceous birds in the same holding, indicating that the H5N2 LPAI isolate was not fully adapted to these two poultry species. Our results highlighted limitations to only using serological screening for the early detection of LPAI in an 'at-risk farm', suggesting that virological and serological monitoring tests be applied simultaneously as a means of testing animals in 'at-risk farms'. </AbstractText><CopyrightInformation>© 2013 Blackwell Verlag GmbH.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Marché</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Avian Virology and Immunology Unit, Veterinary and Agrochemical Research Center, Brussels, Belgium.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Van Borm</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Lambrecht</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Houdart</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>van den Berg</LastName><ForeName>T</ForeName><Initials>T</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>01</Month><Day>24</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Transbound Emerg Dis</MedlineTA><NlmUniqueID>101319538</NlmUniqueID><ISSNLinking>1865-1674</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001530" MajorTopicYN="N">Belgium</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001717" MajorTopicYN="N">Birds</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName><QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004797" MajorTopicYN="N">Enzyme-Linked Immunosorbent Assay</DescriptorName><QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006386" MajorTopicYN="N">Hemagglutination Tests</DescriptorName><QualifierName UI="Q000662" MajorTopicYN="N">veterinary</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053125" MajorTopicYN="N">Influenza A Virus, H5N2 Subtype</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005585" MajorTopicYN="N">Influenza in Birds</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011201" MajorTopicYN="N">Poultry Diseases</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">H5</Keyword><Keyword MajorTopicYN="N">case report</Keyword><Keyword MajorTopicYN="N">influenza diagnosis</Keyword><Keyword MajorTopicYN="N">notifiable avian influenza</Keyword><Keyword MajorTopicYN="N">serological screening</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2012</Year><Month>05</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>1</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>1</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>6</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23347839</ArticleId><ArticleId IdType="doi">10.1111/tbed.12056</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Belgique</li></country><region><li>Région de Bruxelles-Capitale</li></region><settlement><li>Bruxelles</li></settlement></list><tree><noCountry><name sortKey="Houdart, P" sort="Houdart, P" uniqKey="Houdart P" first="P" last="Houdart">P. Houdart</name><name sortKey="Lambrecht, B" sort="Lambrecht, B" uniqKey="Lambrecht B" first="B" last="Lambrecht">B. Lambrecht</name><name sortKey="Van Borm, S" sort="Van Borm, S" uniqKey="Van Borm S" first="S" last="Van Borm">S. Van Borm</name><name sortKey="Van Den Berg, T" sort="Van Den Berg, T" uniqKey="Van Den Berg T" first="T" last="Van Den Berg">T. Van Den Berg</name></noCountry><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Marche, S" sort="Marche, S" uniqKey="Marche S" first="S" last="Marché">S. Marché</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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